Scientists may have finally found what sparks the inflamed and reddened skin in people suffering from rosacea: tiny mites that crawl across most of our faces, unseen and unfelt. The new finding may eventually lead to more effective treatments, researchers say.
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BEIJING, Aug. 31, 2012 /PRNewswire-Asia/ -- UTStarcom Holdings Corp. ("UTStarcom" or "the Company") (NASDAQ: UTSI), a leading provider of Broadband equipment and solutions, today announced that on August 31, 2012 the Company successfully closed the previously announced divestiture of its IPTV business. Simultaneous with the closing, Mr. William Wong has assumed the positions of UTStarcom's Chief Executive Officer and director on the Board of Directors. In addition, Mr. Xiaoping Li, Lead Independent Director, has been elected as Chairman of the Board by the Directors of the Company.
UTStarcom announced its intention to divest its IPTV equipment business on July 27, 2012 as part of a Board plan to transition the Company into higher growth, more profitable areas that the Board believes will enhance the value of the business. With the closure of the divestiture, the IPTV equipment business has become a privately-held, standalone company. Upon meeting the requirements for discontinued operations, UTStarcom will report results from the IPTV division separately as discontinued operations in the third quarter of 2012 and for all comparable periods. Also, Mr. Jack Lu has left UTStarcom as planned in order to lead the IPTV equipment business. Mr. Lu has also resigned from the Company's Board of Directors.
Mr. William Wong assumed the CEO position in line with a previously announced management transition that temporarily named him as Chief Operating Officer. Mr. Wong brings more than 25 years of technology sector experience and has served in many executive positions, including as Chief Executive Officer of Borqs International, which produces software platforms for mobile operators and chip manufacturers. He also served on UTStarcom's Board from September 2010 until December 2011.
"The completion of this transaction is a significant milestone for UTStarcom," said Mr. Xiaoping Li, Chairman of the Board. "It is an important step in streamlining the Company's product portfolio in favor of a dynamic set of businesses. We are pleased to complete it according to the timeline we originally envisioned, and to move on to the next phase of the Company's transformation."
"We welcome Mr. Wong as UTStarcom's new CEO," continued Mr. Li. "He has been instrumental in developing the strategic initiatives we have taken to date, and has demonstrated long-term thinking that will be invaluable in leading UTStarcom to new levels of success. Also, we thank Mr. Lu for his leadership and wish him every success in developing the IPTV business into a market leading technology and service provider."
Mr. William Wong, UTStarcom's new CEO, stated, "I am honored and excited to lead UTStarcom through its business transformation and build a more growth oriented business. We have taken an important step in closing the IPTV divestiture, but it is only the first step. I look forward to working with the Board and management team to find new ways of providing value to our customers and generating returns for our shareholders."
About UTStarcom Holdings Corp.
UTStarcom is a leading provider of Broadband equipment and solutions for cable and telecom operators. The Company sells its solutions to operators in both emerging and established telecommunications and cable markets around the world. UTStarcom enables its customers to rapidly deploy revenue-generating access services using their existing infrastructure, while providing a migration path to cost-efficient, end-to-end IP networks.
UTStarcom was founded in 1991 and listed on the NASDAQ in 2000. With a new management team in 2011, the Company deployed a revamped growth strategy that concentrates on providing media operation support services. UTStarcom has its operational headquarters in Beijing, China and research and development operations in China and India. For more information about UTStarcom, visit the Company's Web site at http://www.utstar.com.
Safe Harbor Statement
This release includes forward-looking statements, including statements regarding the Company's transition into a higher growth business and expectations regarding the accounting for the IPTV divestiture. These statements are forward-looking in nature and subject to risks and uncertainties that may cause actual results to differ materially. These include risks and uncertainties regarding the Company's ability to deliver and capitalize on the opportunities of the higher growth business, to realize anticipated benefits of the divestiture, to execute on its business plan and to manage regulatory matters as well as risk factors identified in its latest Annual Report on Form 20-F and Current Reports on Form 6-K as filed with the Securities and Exchange Commission. The Company is in a period of transition and the conduct of its business is exposed to additional risks as a result. All forward-looking statements included in this release are based upon information available to the Company as of the date of this release, which may change, and UTStarcom assumes no obligation to update any such forward-looking statement.
1 of the best Joplin, Missouri construction website of 2012 rises to meet growing demand for home remodeling and custom home building.
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Joplin, MO -- August 30th, 2012, The real estate rebound and surge in demand for quality Missouri general contractor services seem perfectly timed to coincide with the makeover of one of the area's leading construction firm's websites. The latest National Association of Homebuilders (NAHB) survey this August reveals home builder confidence rising to a new 5 year high, a level we haven't seen since the market went bust in 2007.
Joplin, MO is definitely riding the new real estate wave with the local median home price up 10 percent year-over-year according to data compiler Trulia, while the region continues to boast one of the lowest foreclosure rates in the nation. In fact RealtyTrac reports just 1 in every 32,684 homes in Joplin received a notice in July 2012, beating out the state average of 1 in 1,166, while other states see foreclosures hitting one in every 300. Recent market factors have increased the demand for home remodeling, renovation projects and custom new construction.
However, as with the rest of the real estate industry there has been a big shake up in general contractor services and it can be difficult to find an established and reliable construction firm that can be counted on today. Fortunately for those in Joplin there is one Missouri construction firm which sticks out. While others have abandoned the business during the slump or took years off, Mike Treaster has maintained a reputation as one of Hannibal and Joplin's general contractors who can be counted on.
Mike understands the hard times many MO residents have been through and appreciates what it takes to run a company through tighter times. He loves telling of how he bootstrapped his new business back in 1998 to get it off the ground and build it to where it is today. Mike's motto of "give the customer the best job, with a solid guarantee and you have a customer for life" seems to have served his construction company well. Today Mike's Construction provides full service contracting services for both commercial and residential projects including remodeling, custom building, roofing, excavation, concrete construction and more.
In addition to being considered one of the best Joplin Missouri construction website of 2012 Mike's Construction holds an A+ rating with the Better Business Bureau, is an EPA certified renovation firm, is a member of the National Roofing Contractors Association and is of course licensed and insured. The company is open 7 days a week and that require general contractor assistance or who are contemplating construction or renovation work can request free estimates via the revamped website at http://www.mikesconstructionllc.com, or Calling Mike directly at 888-231-6804.
Contact: Mike Treaster Mikes Construction, LLC 134 Hwy 61 Ste 4, Hannibal Missouri United States 63401 mike@mikesconstructionllc.com 888 231 6804 http://www.mikesconstructionllc.com/ ###
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There is no freedom from discrimination based on having premarital sex, but there is a right to be free of pregnancy discrimination. It may seem odd, but employers can technically fire someone for behavior that doesn?t meet the employer?s ?moral? standards as long as no other protected characteristic is involved.
Recent case: Jarretta was hired to teach at a Christian school. She got pregnant and immediately married her fianc?. She told her supervisors she was expecting and requested maternity leave. According to Jarretta, their response was to lament having to find a substitute teacher.
Jarretta was then fired after also admitting she had committed sin by having sex before marriage. She sued, alleging pregnancy discrimination.
The school said it hadn?t fired her because she was pregnant, but because she had sinned and there were ?consequences for disobeying the word of God.?
The 11th Circuit Court of Appeals ordered a trial. While discrimination based on having premarital sex isn?t prohibited under Title VII, pregnancy discrimination is. The court thought the evidence might point in either direction.
Since juries decide the facts, they will have to decide who is telling the truth. Was Jarretta fired for having sex outside marriage or for incon??veniencing the school by getting pregnant and needing leave? (Hamil??ton v. Southland Christian School, No. 11-13696, 11th Cir., 2012)
Final note: The court didn?t consider the so-called ministerial exception in this case because the school didn?t bring up the issue early enough.
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BEIJING ? Construction laborer Yi Jichun has never heard of Illinois or Iowa. But the migrant worker's favorite comfort food comes straight out of the U.S. Midwest: soybean oil.
The world's biggest consumers of edible oils, Chinese households have developed a taste for the stuff that would make a county fair fry cook proud. Be it a simple stir-fry, poached fish or deep-fried pork ribs, many Chinese diners love their grub covered in an oily sheen. Jugs of the golden liquid make popular gifts for Chinese New Year.
"Without the oil, it would taste too plain," Yi said as he tucked into a lunch of sliced cucumbers and chicken drumsticks slathered with grease. "I wouldn't want to finish it."
And that has officials in Beijing worried. The worst U.S. drought in half a century is sending global grain prices soaring. The fallout is almost certain to be felt at dinner tables across China. The No. 1 foreign buyer of American soybeans, which are pressed into cooking oil and used for animal feed, China last year purchased about half of U.S. exports, more than $10.4 billion worth, according to the American Soybean Assn. China has also stepped up purchases of U.S. corn and wheat to feed the nation's growing appetite.
Poor U.S. harvests could fuel Chinese food inflation and social discontent. China has already begun tapping its grain reserves to ensure price stability. The government has ordered the nation's biggest cooking oil producers twice in recent months to keep their prices in check. And it's scouring the globe for alternative supplies.
It won't be easy. More than two-thirds of cooking oil consumed in China comes from soybeans, and most of those soybeans are supplied by the U.S., according to Ma Wenfeng, an analyst with Beijing Orient Agribusiness Consultant Co. For now, Chinese consumers are bound to the fortunes of farmers in the American heartland.
"Soybean oil is the most important edible oil in China ... which makes us vulnerable to the drought" gripping the U.S., Ma said.
Retail prices have so far held steady. A standard 5-liter jug (1.32 gallons) of edible oil in China averages about $9.76 today, only 24 cents more than at the beginning of the year, Ma said.
But that could change if the U.S. soybean harvest proves especially weak. Prices have risen about 40% since January to more than $16 a bushel.
Expensive grain means higher costs for animal feed, which leads to pricier meat, milk and eggs. That's especially tough on people in developing countries. In China, consumers devote more than one-fifth of their monthly income to food, about three times more than their American counterparts, according to the USDA.
That's "why authorities get concerned about social stability," said Alistair Thornton, a Beijing-based analyst for IHS Global Insight. "Inflation has a long history of sparking discontent, so obviously it's on the forefront of the Chinese leadership's mind."
Rising Chinese incomes in recent years have fueled a surge in meat consumption. Ditto for cooking oil, which a few decades ago was rationed with food stamps. Fan Zhihong, a nutrition expert at China Agricultural University in Beijing, said that's leading to more obesity and heart disease.
"With economic development, people now have enough money for cooking oil. So they spoil themselves by using lots and making their food delicious," Fan said. "They'll even make a healthy dish of dark leafy greens into a fatty dish."
An artery-clogging sample of Beijing's local treats includes pai cha (crispy fried dough), xian bing (fried pancakes stuffed with pork and chives) and zha jiang mian (room temperature noodles topped with bean paste that often arrives submerged in half an inch of clear grease).
"It tastes better when it's fried," said Li Yuanying, 25, espousing a universal truth as she purchased deep-fried vegetable balls at aWal-Martcooked food counter in Beijing's central business district.
Before her was a shiny selection of fried chilies, fried peanuts, fried crullers, fried pancakes and fried sesame balls. Nearby, stacked high against a wall, was an arsenal of cooking oils that would have made Southern cooking star Paula Deen feel right at home. In addition to soybean oil, there were large jugs of peanut, corn, rapeseed, palm, tea seed and fish oils.
"I tell our board members that it reminds me of the cereal aisle in the U.S.," said Paul Burke, the Beijing-based regional director of the U.S. Soybean Export Council.
Prices ranged from $7.40 for 5 liters of soybean oil to $19.35 for a blend of olive and sunflower oils. In the U.S., such quantities might be suitable for restaurant owners or, say, someone deep-frying a turkey. But in China, they're a staple of the family grocery list.
"This may last me a little more than a month," said a senior citizen who purchased soybean oil because it was still cheaper than many of the alternatives.
Rising prices could be one way to get Chinese consumers to scale back on greasy food. But some cooks said they'll believe it when they see it.
"Everything needs oil," said a Beijing steamed bun vendor who gave only his surname, Chen. "Especially the vegetarian buns. If you don't put oil, it won't taste good."
david.pierson@latimes.com
Nicole Liu and Tommy Yang in The Times' Beijing bureau contributed to this report.
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The "cancerous tumour" of Israel is the biggest problem confronting Muslim countries today, Iran's supreme leader said on Sunday, repeating an epithet slammed just days earlier by UN chief Ban Ki-moon and US and EU officials.
In a speech marking Eid al-Fitr, the end of the Muslim holy month of Ramadan, Ayatollah Ali Khamenei said "the big powers have dominated the destiny of the Islamic countries for years and... installed the Zionist cancerous tumour in the heart of the Islamic world," according to the official IRNA news agency.
"Many of the Islamic world's problems come from the existence of the sham Zionist regime," he was quoted as saying.
The "tumour" characterisation was a repeat of terms Khamenei and President Mahmoud Ahmadinejad have long used to portray Israel as an illegitimate state in the Middle East that will inevitably disappear.
In the most recent incidents, last Wednesday Khamenei called Israel a "bogus and fake Zionist outgrowth" and Ahmadinejad on Friday said: "The Zionist regime and the Zionists are a cancerous tumour."
Those expressions were met with condemnation on Friday by the UN's Ban, the United States, EU foreign policy chief Catherine Ashton and France's foreign ministry.
Ban, whom Iran has invited to attend a summit in Tehran at the end of the month, was "dismayed" by the "offensive and inflammatory statements," according to his spokesman.
Ashton's office and a spokesman for the US National Security Council both slammed the remarks as "hateful", while a French foreign ministry spokesman said they were "outrageous and totally unacceptable."
In his speech on Sunday to top Iranian officials and Muslim ambassadors in Tehran, Khamenei said the issue of Israel and its control over the Palestinian people was the main problem for Islamic countries.
"All Islamic governments and people have to pay attention to the very dangerous plot (by the West) that seeks to obscure this issue by creating divisions within the Islamic nation," he was quoted as saying.
He accused the world's "big powers" of using "the old method of 'divide and conquer'" on Islamic states, but said the popular revolts shaking the Arab world were changing the situation.
Tensions between Israel and Iran are taut because of threats by the Jewish state to attack nuclear facilities in the Islamic republic to prevent it reaching the capability to produce nuclear weapons.
Israel and its ally, the United States, accuse Iran of seeking to develop an atomic arsenal.
Tehran denies that, and says its nuclear programme is exclusively peaceful. Its military chiefs warn they will destroy Israel if it attacks.
On Saturday, General Amir Ali Hajizadeh, the head of the aerospatial division of the Revolutionary Guards that is in charge of Iran's missiles, said: "Iran's response to any aggression will be rapid, firm, destructive and broad."
He said he welcomed Israel making such a move, as "that would be a good occasion and good pretext to put an end to the shameful existence of the sham, occupying and usurping regime and save humanity from this cancerous tumour."
Malware looking for banking details could be greatest threat facing Android users, says Kaspersky
If there was any doubt that Android is the prime target for cyber criminals looking to exploit the mobile boom, figures from Kaspersky Lab should put a stop to that.
The company's research has revealed threats aimed at Android devices tripled in the second quarter. Over the three months to the end of June Kaspersky spotted 14,923 new threats. The previous quarter saw just 5,441 new threats detected.
Just under half of the new threats detected were Trojans that aim to steal data from the device, such as contact names, email addresses and telephone numbers.
Around one-quarter were of the more serious variety - SMS Trojans. These malware sign users up to premium rate text services without their knowledge or consent. The cost to the unsuspecting user can be astronomically high.
Interestingly Kaspersky said that the geographical reach of these programs is growing. A few years ago they were only detected in Russia, China and parts of south east Asia. Today the company claims it is detected them in 47 different countries.
A relatively new but growing issue for Android devices is backdoors, which currently make up 18% of all Android threats detected. These can give cyber criminals full access to a user's device. At the moment they are primarily being used to build a network of mobile bots which can be used to launch spam and malware attacks.
There is another threat that is currently small but growing on the radar - that of Spy Trojans. Kaspersky said these present the greatest threat to Android users as they can steal banking information.
However, recent figures have suggested that mobile banking is failing to gain traction in the UK market, meaning Kaspersky's fears could be misguided.
Research from YouGov found that 80% of users are yet to embrace mobile banking while 58% show no interest at all in a mobile wallet. Over half of those surveyed feared their banking details would not be safe with mobile banking.
It is no surprise to see cyber criminals turning their attention to Android. Recent figures from Gartner revealed that mobile devices running Google's mobile OS shipped 98.5 million units in Q2 2012, more than three times the number of Apple iOS devices. Android sales continue to be dominated by Samsung's range of smartphones, totalling 46% of the Android market.
"In the near future, we expect not only more malware, but more effective and dangerous malware targeting Android," said Yuri Namestnikov, senior malware analyst at Kaspersky Lab. "Judging from existing trends, we should expect that cybercriminals will soon shift to more personalised attacks. This is primarily about malware hunting for confidential data with which to steal money from users' credit cards."
In that case, you should try to enroll into and online course designed by the famous sexologist Dr. Gabrielle Morissey. The online course is offered by Lifestyle Learning Direct entitled Love, Sex and Relationships ?tutored. The course focuses on the relationship between couples and how they can rekindle the flame in their relationship. It covers topics that help you to communicate better even in bed. Topics such as importance of sex, sexual response and libido, sexual techniques and sexperimenting are discussed to add spice to your relationship. Aside from reading materials, this course also includes activities, personal challenges, reflection paper, fun quizzes and exercises to make sure that you enjoy as you learn more about you and your partner. The course is done online so you can do it within the comforts of your home. You will surely have no problems when it comes to scheduling because they have a flexible time schedule. You will also have a tutor that will keep track of your progress. After this course, there is no doubt that you and your partner will start dating again. It will be just like how you started. Your sex life will definitely improve a lot. It will keep the fire burning in your relationship.
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ScienceDaily (Aug. 17, 2012) ? Uncoupling proteins present a paradox. They are found within mitochondria and serve to prevent the cell's powerhouses from exploiting the charge differential across their membranes to generate ATP, which the body uses as an energy source. When uncoupling proteins are active, mitochondria produce heat instead of ATP. This may be useful under certain circumstances, such as when an animal is hibernating, but it seems unlikely that helping bears through the winter is the only function of uncoupling proteins, especially as non-hibernating animals also have them. Particularly poorly understood is the uncoupling protein UCP2, to which no function has yet been assigned. Elena Pohl and colleagues at the University of Veterinary Medicine, Vienna now show that the protein occurs mainly in cells of the immune system and that its level increases when T cells are stimulated to become active. The results strongly suggest that UCP2 is somehow involved in the immune response.
The group's highly provocative findings are published in the online journal PLoS ONE.
Mitochondria represent the powerhouses of the eukaryotic cell. They are able to use the primary product of the breakdown of sugars to generate a proton gradient across their inner membrane and to exploit this gradient to produce ATP, which drives cellular metabolism. The importance of mitochondria to higher life forms is clear from what happens when their function is blocked: many poisons, such as cyanide, are known to act in this manner.
In this light, the discovery in 1973 of a eukaryotic protein that dissipates the proton gradient without generating ATP was highly unexpected. When this protein, thermogenin, is active, mitochondria produce heat rather than ATP. We now know that thermogenin is merely one member of a family of so-called 'uncoupling proteins' that can use proton gradients to generate heat. The founder member of the family, thermogenin, has been renamed uncoupling protein 1 or UCP1 and is known to be important in helping animals keep warm during hibernation and for babies to maintain their body temperature. The actions of the other members of the family are less well understood. Particularly enigmatic is UCP2 but important clues to its function have now been provided by Anne Rupprecht and colleagues in the Institute of Physiology at the University of Veterinary Medicine, Vienna. Together with collaboration partners in Germany and Sweden, the researchers carefully examined the distribution of the UCP2 protein in mice. Their results showed clearly that UCP2 was preferentially expressed in cells related to the immune system and not, as generally believed, in neurons.
The implication was that UCP2 might somehow be involved in immune function. This surprising idea was tested by examining the change in UCP2 levels in T cells that were stimulated into action by a specific antigen. Stimulation indeed caused an increase in the amount of UCP2 in the cells. This was paralleled by increases in the concentrations of other proteins known to be produced in response to T-cell activation. When the cells were further stimulated seven and fourteen days later the amount of UCP2 increased although the amounts of the other proteins investigated did not.
It is attractive to speculate that the increase in UCP2 might be involved in signalling T-call stimulation but Pohl is quick to quash the notion. "Anne showed that the increase in UCP2 only starts a few hours after activation of T cells, while other events are seen much sooner. UCP2 thus arrives too late to be involved in stimulating the cells, so the increase must be related to overall metabolic changes in proliferating cells. This fits with our observation that UCP2 is not found in neurons, which no longer proliferate" In other words, although we still cannot be sure of the exact function of this intriguing protein, "at least we now know where to start looking!" And the finding that UCP2 is required by fast proliferating cells may have important consequences for the development of treatments for immune disorders, such as autoimmune and neurodegenerative diseases, and perhaps also for other diseases where cells divide rapidly, such as cancer.
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The above story is reprinted from materials provided by Veterin?rmedizinische Universit?t Wien.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Anne Rupprecht, Anja U. Br?uer, Alina Smorodchenko, Justus Goyn, Karolina E. Hilse, Irina G. Shabalina, Carmen Infante-Duarte, Elena E. Pohl. Quantification of Uncoupling Protein 2 Reveals Its Main Expression in Immune Cells and Selective Up-Regulation during T-Cell Proliferation. PLoS ONE, 2012; 7 (8): e41406 DOI: 10.1371/journal.pone.0041406
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
ScienceDaily (Aug. 17, 2012) ? A team of evolutionary biologists compared the anatomy and genes of bats to help solve a persistent question in evolution: Why do analyses of different features of an organism result in conflicting patterns of evolutionary relationships? Their findings, "Understanding phylogenetic incongruence: lessons from phyllostomid bats," appear in the August 14 edition of Biological Reviews.
To answer this question, Liliana D?valos, PhD, Assistant Professor in the Department of Ecology and Evolution, and member of the Consortium for Inter-Disciplinary Environmental Research (CIDER) at Stony Brook University, and Andrea Cirranello of the Division of Vertebrate Zoology at the American Museum of Natural History (AMNH), together with colleagues at the AMNH and the New York College of Osteopathic Medicine, examined the skin, skeleton, muscle, tongue, internal organs and a few genes of a family of New World bats, applying statistical models to uncover the genetic and anatomical features that produced the conflicts between evolutionary patterns. This work was funded in part by the National Science Foundation.
Specifically, the team examined why genes suggested that nectar feeding had evolved twice in Leaf-Nosed bats, while the anatomical features strongly pointed to a single origin of nectar feeding in this group. Most bats feed on insects, but New World Leaf-Nosed bats are exceptionally diverse in that they feed on nectar, fruit, frogs, lizards and even blood.
One hypothesis that the team tested is that traits linked to how bats feed have been shaped by natural selection for a nectar-based diet, resulting in the conflicting pattern. As D?valos and Cirranello explain, connecting the conflicting pattern to the diet requires showing that the evolutionary pattern resulting from anatomical traits is wrong, and that the traits producing the conflict with the genetic data are linked to a shared dietary specialization.
"If a diet specializing in nectar helped shape the anatomy of the two groups of bats, then the traits that support the groups coming together should be related to feeding, and taking those traits out should break up the spurious group of nectar-feeding bats," the researchers said. They found support for these predictions by analyzing evolutionary trees from two genomic data sets, alongside trees based on more than 200 anatomical traits; and applying a battery of statistical approaches to identify where in the evolutionary tree the conflicts arose and what genetic regions and traits supported the differences.
The team traced the conflict in evolutionary patterns among nectar-feeding bats to traits linked to feeding, such as the shape and number of teeth, gaining a "paintbrush" type tongue tip, and rearranging the tongue muscles to accommodate longer, extensible tongues. All of these traits are thought to be associated with specialized nectar feeding. The grouping of all nectar-feeding bats broke down into smaller groups when those traits were taken out of the analyses. Overall, the team found that anatomical traits and the studied genes tended to agree on many parts of the evolutionary tree, but that the anatomical traits associated with nectar feeding brought nectar-feeding bats together.
Natural selection has shaped the anatomy of organisms, but when specializations evolved long ago, it can be difficult for evolutionary biologists to demonstrate that traits bear its signature. By ruling out other biological processes that produce conflict among evolutionary trees, and tracing the conflict to specific traits that are known to enable drinking nectar, the team was able to narrow the options and discover patterns consistent with the signature of adaptation to diet. "We found that anatomical traits associated with nectar feeding have evolved and been lost several times, so they tend to bring bats from different branches of the evolutionary tree together, in direct conflict with genetic trees," D?valos and Cirranello said.
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Journal Reference:
Liliana M. D?valos, Andrea L. Cirranello, Jonathan H. Geisler, Nancy B. Simmons. Understanding phylogenetic incongruence: lessons from phyllostomid bats. Biological Reviews, 2012; DOI: 10.1111/j.1469-185X.2012.00240.x
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Tim and Brian are back in New York and will be joined by Dana once again to discuss the week that was. The magic will happen at 5PM ET, after the break.
We regularly hear calls to improve ?ocean health.? Health is a powerful metaphor, but scientists have had no way to measure it and therefore no means to evaluate how the world's oceans are doing. More than 60 researchers from a cross section of disciplines and institutions, including the National Center for Ecological Analysis and Synthesis (NCEAS) at the University of California, Santa Barbara, have created the Ocean Health Index to do just that. It rates the health of ocean waters bordering 171 coastal countries and territories. Each nation's overall score is the average of scores for 10 widely held public goals for healthy oceans, including sustainable food provision, recreation, fishing opportunities and biodiversity.
The index, which was published in August in Nature, is not a measure of how pristine the ocean is. (Scientific American is part of Nature Publishing Group.) Instead it measures how sustainably the ocean is providing the things people care about. The goals are universal measures of ecosystem health?all 10 must be met for a country's ocean to be rated as healthy?but the relative importance of each goal can vary from place to place.
Factoring human goals into assessments of ocean health is a radical departure from traditional conservation approaches. Yet public policy and conservation organizations worldwide are rapidly converging on the view that people are now a fundamental part of every ecosystem on the earth, and any effective management strategy must embrace this reality. If we focus only on excluding people from nature, conservation plans are doomed to fail.
The index is an important first step. Countries cannot make progress on ocean health without first knowing where they stand. In that sense, the index is a key benchmark. Later this year the NCEAS and various partners will test its application in the U.S., Fiji and Brazil. Policy makers and managers could use the index to guide decision making?for example, about whether offshore wind energy should be expanded in the U.S., whether land or ocean conservation measures will benefit coral reefs in Fiji and how marine-zoning plans in Brazil might affect overall ocean health.
Of course, various people or adjacent countries might put different priorities on different goals. As a tool that lays them all out, the index can aid any negotiations by identifying trade-offs and synergies.
If you're staying anywhere within or around California, you've quite possibly been aware of the California Solar Initiative (CSI). If you intend on going solar with your rooftop, then it's critical that you know the best way the CSI can be of service. As solar panels and systems don't come cheap, under the CSI, California citizens can have their own solar roofing system for a lower cost.
The CSI is among the fruits of the Go Solar California initiative, a joint endeavor of the California Public Utilities Commission and the California Energy Commission. This drive for solar power intends to set up a minimum of 3,000 megawatts of photovoltaic panels and systems in California houses and business establishments by 2016. The CSI is anticipated to accomplish over half of the total objective by installing a minimum of 1,940 megawatts of solar systems. What superior technique to achieve this target and support engagement than with a kickback?
Similar to a gratified teacher presenting star students an award, the CSI applies two kinds of incentive programs. First is the Performance Based Incentive (PBI), applicable for sizable commercial projects or government organizations. The incentive will be hinged on actual efficiency of the employed solar system (as meant by the name itself) or the real energy output. Incentive will be discharged in a span of 5 years.
If you're planning to go solar Concord pros are suggesting today is the right time considering that you might simply qualify for the other type of incentive, the Expected Performance Based Buydown (EPBB). The EPBB is applicable for homes in addition to small business units and functions by determining the assumed performance of solar systems. Location and configuration of the panels are just a few of the factors that will be thought of in the measurement. Unlike the installment payment method of the PBI, EPBB incentive payout is one-time only.
As of 2011, accessible information displays that the CSI has put up a total of 468 megawatts and has paid over $ 700 million worth of kickbacks. Contra Costa county, where Concord is situated, has at least 43.4 megawatts of solar panels mounted. You still have time to communicate with a solar company California locals can recommend so that you also can go solar.
For further details about the CSI and other solar energy projects, you can check out the Go Solar California website at GoSolarCalifornia. ca. gov. For details about the best way solar energy can help you and your house, consult the best solar companies in California.
For more details, search best solar companies in california, solar concord and solar company California in Google for related information.
Keywords: best solar companies in california, solar concord, solar company California
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JDRF-Helmsley Charitable Trust to fund islet encapsulation research at Diabetes Research Institute Public release date: 16-Aug-2012 [ | E-mail | Share ]
Contact: Michael Cook mcook@jdrf.org 212-479-7510 JDRF
Researchers from both institutions hope to improve long-term effectiveness of islet cell transplantation
New York, NY, August 16, 2012 JDRF, in collaboration with The Leona M. and Harry B. Helmsley Charitable Trust (HCT), announced today that it has finalized a grant in the area of islet cell encapsulation to Dr. Camillo Ricordi, M.D. and a team of investigators at the Diabetes Research Institute (DRI), based at the University of Miami (FL).
Performed at the DRI since the 1980s, successful islet cell transplants give patients with type 1 diabetes (T1D) the ability to naturally produce their own insulin and lead healthier, more independent lives. However, only a small number of patients benefit from the procedure because of a shortage of cadaver islets, problems associated with the need for chronic immunosuppression drugs, and the low survival rate of islets immediately following implantation. The current transplant site, the liver, can be particularly inhospitable for newly implanted islets, leading to hypoxia (low oxygen) and inflammation. The number of transplants available to patients is also limited by the small number of donors and the large number of cells required for each procedure.
In the $4.6 million grant proposal being funded jointly by the JDRF-Helmsley Charitable Trust over three years, Dr. Ricordi's team will attempt to address the limitations of the requirements for immunosuppression, and the poor viability of islets, beginning with an alternate site of implantation. While the research community is exploring multiple possible alternatives, the DRI has chosen to pursue a fold in the lining of the abdomen called the omentum that the team believes will allow better access for the procedure, offer more space to accommodate delivery systems, and provide a safer environment for the newly-implanted cells.
"This is a critically important and timely support that will allow our team to remain focused on the path to a biologic cure for diabetes," Dr. Ricordi said. "The overall goal is to use a multipronged approach to address and resolve all of the outstanding issues in islet transplantation and move the field to the next level of success."
The other problem that Dr. Ricordi's team is attempting to solve is protecting the implanted cells from the body's immune response. Their approach to immunoprotection is two-fold. They will use a bioactive scaffold as a delivery system for the implanted islets that is designed to protect them from the immediate immune response. The scaffold allows the islet cells access to the surrounding blood vessels to prevent poor oxygenation, which will allow better regulation of blood sugar levels. The team is also engineering a conformal coating to encapsulate each islet to further promote long-term survival. Ultimately, the scaffold could be used to modify the immune cells in the implant local area, offering maximum protection. If successful, such technologies could remove the need for immunosuppression drugs and ensure long-term survival for the implanted cells.
"We are very excited to be supporting Dr. Ricordi's lab for this research," said JDRF Chief Scientific Officer Dr. Richard Insel. "Dr. Ricordi and colleagues have been pioneers in the area of islet cell transplantation and encapsulation, and we feel that they are well-positioned to advance an area that we hope will bring a real benefit to individuals with type 1 diabetes."
###
About JDRF
JDRF is the leading global organization focused on type 1 diabetes (T1D) research. Driven by passionate, grassroots volunteers connected to children, adolescents, and adults with this disease, JDRF is now the largest charitable supporter of T1D research. The goal of JDRF research is to improve the lives of all people affected by T1D by accelerating progress on the most promising opportunities for curing, better treating, and preventing T1D. JDRF collaborates with a wide spectrum of partners who share this goal.
Since its founding in 1970, JDRF has awarded more than $1.6 billion to diabetes research. Past JDRF efforts have helped to significantly advance the care of people with this disease, and have expanded the critical scientific understanding of T1D. JDRF will not rest until T1D is fully conquered. More than 80 percent of JDRF's expenditures directly support research and research-related education.
For more information, please visit www.jdrf.org.
About The Leona M. and Harry B. Helmsley Charitable Trust
The Leona M. and Harry B. Helmsley Charitable Trust, established in 1999, is administered by four Trustees selected by Leona Helmsley. As a continuation of Mr. and Mrs. Helmsley's generous giving throughout their lifetimes, the Trust supports a diverse range of organizations with a major focus on health and medical research, in addition to programs in human services, education, cultural access, conservation and the security and development of Israel. Since 2009, the Trust has committed over $100 million to type 1 diabetes research and programs through the Helmsley Type 1 Diabetes Program. For more information, please visit www.helmsleytrust.org.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
JDRF-Helmsley Charitable Trust to fund islet encapsulation research at Diabetes Research Institute Public release date: 16-Aug-2012 [ | E-mail | Share ]
Contact: Michael Cook mcook@jdrf.org 212-479-7510 JDRF
Researchers from both institutions hope to improve long-term effectiveness of islet cell transplantation
New York, NY, August 16, 2012 JDRF, in collaboration with The Leona M. and Harry B. Helmsley Charitable Trust (HCT), announced today that it has finalized a grant in the area of islet cell encapsulation to Dr. Camillo Ricordi, M.D. and a team of investigators at the Diabetes Research Institute (DRI), based at the University of Miami (FL).
Performed at the DRI since the 1980s, successful islet cell transplants give patients with type 1 diabetes (T1D) the ability to naturally produce their own insulin and lead healthier, more independent lives. However, only a small number of patients benefit from the procedure because of a shortage of cadaver islets, problems associated with the need for chronic immunosuppression drugs, and the low survival rate of islets immediately following implantation. The current transplant site, the liver, can be particularly inhospitable for newly implanted islets, leading to hypoxia (low oxygen) and inflammation. The number of transplants available to patients is also limited by the small number of donors and the large number of cells required for each procedure.
In the $4.6 million grant proposal being funded jointly by the JDRF-Helmsley Charitable Trust over three years, Dr. Ricordi's team will attempt to address the limitations of the requirements for immunosuppression, and the poor viability of islets, beginning with an alternate site of implantation. While the research community is exploring multiple possible alternatives, the DRI has chosen to pursue a fold in the lining of the abdomen called the omentum that the team believes will allow better access for the procedure, offer more space to accommodate delivery systems, and provide a safer environment for the newly-implanted cells.
"This is a critically important and timely support that will allow our team to remain focused on the path to a biologic cure for diabetes," Dr. Ricordi said. "The overall goal is to use a multipronged approach to address and resolve all of the outstanding issues in islet transplantation and move the field to the next level of success."
The other problem that Dr. Ricordi's team is attempting to solve is protecting the implanted cells from the body's immune response. Their approach to immunoprotection is two-fold. They will use a bioactive scaffold as a delivery system for the implanted islets that is designed to protect them from the immediate immune response. The scaffold allows the islet cells access to the surrounding blood vessels to prevent poor oxygenation, which will allow better regulation of blood sugar levels. The team is also engineering a conformal coating to encapsulate each islet to further promote long-term survival. Ultimately, the scaffold could be used to modify the immune cells in the implant local area, offering maximum protection. If successful, such technologies could remove the need for immunosuppression drugs and ensure long-term survival for the implanted cells.
"We are very excited to be supporting Dr. Ricordi's lab for this research," said JDRF Chief Scientific Officer Dr. Richard Insel. "Dr. Ricordi and colleagues have been pioneers in the area of islet cell transplantation and encapsulation, and we feel that they are well-positioned to advance an area that we hope will bring a real benefit to individuals with type 1 diabetes."
###
About JDRF
JDRF is the leading global organization focused on type 1 diabetes (T1D) research. Driven by passionate, grassroots volunteers connected to children, adolescents, and adults with this disease, JDRF is now the largest charitable supporter of T1D research. The goal of JDRF research is to improve the lives of all people affected by T1D by accelerating progress on the most promising opportunities for curing, better treating, and preventing T1D. JDRF collaborates with a wide spectrum of partners who share this goal.
Since its founding in 1970, JDRF has awarded more than $1.6 billion to diabetes research. Past JDRF efforts have helped to significantly advance the care of people with this disease, and have expanded the critical scientific understanding of T1D. JDRF will not rest until T1D is fully conquered. More than 80 percent of JDRF's expenditures directly support research and research-related education.
For more information, please visit www.jdrf.org.
About The Leona M. and Harry B. Helmsley Charitable Trust
The Leona M. and Harry B. Helmsley Charitable Trust, established in 1999, is administered by four Trustees selected by Leona Helmsley. As a continuation of Mr. and Mrs. Helmsley's generous giving throughout their lifetimes, the Trust supports a diverse range of organizations with a major focus on health and medical research, in addition to programs in human services, education, cultural access, conservation and the security and development of Israel. Since 2009, the Trust has committed over $100 million to type 1 diabetes research and programs through the Helmsley Type 1 Diabetes Program. For more information, please visit www.helmsleytrust.org.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Yesterday, the first trailer for Martin McDonagh's "In Bruges" follow-up, "Seven Psychopaths," debuted and revealed what kind of insanity is in store for us when the film opens nationwide on October 12, shortly after its premiere during TIFF's Midnight Madness. The preview did an excellent job filling us in on just exactly who the titular [...]
Of course advertising your network marketing business will cost money, but how else could you possibly market your product without it? Many network marketers fail to even budget for advertising and consequently they miss the opportunity to make money. Advertising truly is an investment, if you advertise in the right places and these places should be selected cleverly and monitored continually to see if they work. Ineffectual advertising can put you into bankruptcy!
Just like any business online and off, network marketing advertising is one of the keys to success, it can be rather puzzling online particularly with the other millions of internet sites, blogs and adverts all competing against you and unless your product is totally unique and new, you?re going to need to learn where to place your advertising.
If you haven?t already set aside a budget for advertising you need to do so right away, and figure realistically how much you are able to afford on a once per month basis and don?t go over that amount, if you find that your advertising in a certain area is bringing results, you can always increase your budget later .
Most new network marketeers only have a little budget, but that should not be a difficulty, there are numerous effective places to try advertising on the Internet for free, you must experiment with most, and after a set period of time, drop the ones that are not working for you. Pay attention to where you are going to advertise, because advertising in the wrong place can damage your image, and therefore lose you money.
The following are the results which you should attempt to get by looking to advertise your network marketing business:
1. It should be bringing you a torrent of leads 2. It?ll be a medium for you to publicize your service or product 3. It?ll be a technique for branding your company and growing brand recognition 4. It should be a method for you to effectively and efficiency close sales.
By far the best ( and cheapest ) form of advertising is personal recommendation, and online generating a buzz about your product can pay enormous dividends, but it is going to be your decision how you go about doing this. Social networking sites, particularly YouTube, are fantastic places for getting masses of eyes on your product, but although this technique may be free, you should plan everything you do conscientiously or it can backfire.
Twitter has certain laws in its own right, you cannot just jump on there and start shouting about your product ? no-one will take any notice of you. Posting on Twitter each five minutes will also get you ignored, you?ll be branded as a nuisance, better you build a following first. In the physical world you wouldn?t go to your best friend?s wedding and start roaring about your product in the reception, the idea is to build relations in any social media situations.
At the start you could have to depend on others for referrals, which is also an extremely valuable methodology of getting leads both online and off-line. Make a point of developing a relationship with the individual who gives you these referrals. No one is going to hand you what?s essentially a pot of money, without getting something in turn.
Local bricks and mortar firms frequently choose to do direct mail outs, although that habit appeared to die with the previous century, it can be useful. What many businesses do not do is collect valuable info from these mail outs and consequently they do not build a list of possible customers, the drawback being with direct mail outs is that they can be incredibly pricey.
The good thing is, if you can somehow get folk to fill in a card, or leave an email address when they come into your shop or business, time ought to be taken to compile these email addresses into a list for future marketing campaigns, the best way is to give worth for value i.e. Offer something of worth for their email address, which could be a discount or a free dessert whatever?s suitable.
It is difficult to run an efficient network marketing advertising campaign if you actually do not understand how it all works. There?s a great amount of psychology behind selling effectively and if you do not understand the basics of network marketing now is a very good time to learn.
MLM Lead System Pro is one of the most trustworthy marketing systems to have come on the market lately. It gives you helpful info on all sides of network marketing, so you can generate prequalified leads effectively, and also covers network marketing advertising. It is written in a way that new entrants to network marketing and those endeavoring to get their businesses off the ground can understand.